Science

Unlocking Bacterial Defense: How Short Synthetic Nucleic Acids Explore Virus-Inflected Genes

  • RESEARCH BRIEFINGS
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        Earth hosts an incredible variety of biological entities, with bacteriophages (or phages) being the most diverse among them. These viruses that infect bacteria are treasure troves for discovering new proteins and developing biotechnological tools. However, many of the phage-bacteria systems are resistant to genetic manipulation. A promising solution is to silence specific phage genes using short synthetic nucleic acids in a non-genetic manner.
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Summary: This article highlights the diversity of bacteriophages and their potential in biotechnology. It discusses the challenges of manipulating phage-bacteria systems and introduces a novel method of gene silencing using synthetic nucleic acids.

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